Indium-111

Indium-111, 111In
General
Symbol111In
Namesindium-111, 111In, In-111
Protons (Z)49
Neutrons (N)62
Nuclide data
Natural abundancesyn
Half-life (t1/2)2.8049 d[1]
Decay products111Cd
Decay modes
Decay modeDecay energy (MeV)
EC0.860[2]
Isotopes of indium
Complete table of nuclides

Indium-111 (111In) is a radioactive isotope of indium (In). It decays by electron capture to stable cadmium-111 with a half-life of 2.8 days.[3] Indium-111 chloride (111InCl) solution is produced by proton irradiation of a cadmium target (112Cd(p,2n) or 111Cd(p,n)) in a cyclotron, as recommended by International Atomic Energy Agency (IAEA).[4] The former method is more commonly used as it results in a high level of radionuclide purity.

Indium-111 is commonly used in nuclear medicine diagnostic imaging by radiolabeling targeted molecules or cells. During its radioactive decay, it emits low energy gamma (γ) photons which can be imaged using planar or single-photon emission computed tomography (SPECT) gamma cameras (primary energies (ε) of 171.3 keV (91%) and 245.4 keV (94%))[3]

  1. ^ Table of Radionuclides, Vol. 3 (PDF). Bureau international des poids et mesures. 2006. p. 75. ISBN 92-822-2218-7. Retrieved 26 June 2017.
  2. ^ Wang, M.; Audi, G.; Kondev, F. G.; Huang, W. J.; Naimi, S.; Xu, X. (2017). "The AME2016 atomic mass evaluation (II). Tables, graphs, and references" (PDF). Chinese Physics C. 41 (3): 030003-1–030003-442. doi:10.1088/1674-1137/41/3/030003.
  3. ^ a b "FDA Label Document:Indium In-111 Chloride Sterile Solution". www.accessdata.fda.gov. Retrieved 20 Aug 2018.
  4. ^ Takács, S.; Tárkányi, F.; Hermanne, A. (Dec 2005). "Validation and upgrading of the recommended cross-section data of charged particle reactions: Gamma emitter radioisotopes". Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 240 (4): 790–802. Bibcode:2005NIMPB.240..790T. doi:10.1016/j.nimb.2005.06.209. ISSN 0168-583X.

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