Back Radium-223 Czech رادیوم-۲۲۳ Persian Radium 223 French Radium-223 ID ラジウム223 Japanese Radium-223 Dutch เรเดียม-223 Thai
| General | |
|---|---|
| Symbol | 223Ra |
| Names | radium-223, 223Ra, Ra-223, actinium X, AcX |
| Protons (Z) | 88 |
| Neutrons (N) | 135 |
| Nuclide data | |
| Half-life (t1/2) | 11.43±0.05 d |
| Isotope mass | 223.0185007(22) Da |
| Parent isotopes | 227Th 223Fr |
| Decay products | 219Rn |
| Decay modes | |
| Decay mode | Decay energy (MeV) |
| α | 5.979[1] |
| Isotopes of radium Complete table of nuclides | |
Radium-223 (223Ra, Ra-223) is an isotope of radium with an 11.4-day half-life. It was discovered in 1905 by T. Godlewski,[2][3][4] a Polish chemist from Kraków, and was historically known as actinium X (AcX).[5][6] Radium-223 dichloride is an alpha particle-emitting radiotherapy drug that mimics calcium and forms complexes with hydroxyapatite at areas of increased bone turnover.[7] The principal use of radium-223, as a radiopharmaceutical to treat metastatic cancers in bone, takes advantage of its chemical similarity to calcium, and the short range of the alpha radiation it emits.[8]
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- ^ Godlewski T (1905). "A new radio-active product from actinium". Nature. 71 (1839): 294–295. Bibcode:1905Natur..71..294G. doi:10.1038/071294b0. ISSN 0028-0836. S2CID 4047285.
- ^ Godlewski T (1905). "V. Actinium and its successive products". The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science. 10 (55): 35–45. doi:10.1080/14786440509463342. ISSN 1941-5982.
- ^ Hahn O (1906). "A new product of actinium". Nature. 73 (1902): 559–560. Bibcode:1906Natur..73..559H. doi:10.1038/073559b0. ISSN 0028-0836. S2CID 4052127.
- ^ Kirby HW (1971). "The discovery of actinium". Isis. 62 (3): 290–308. doi:10.1086/350760. JSTOR 229943. S2CID 144651011.
- ^ Fry C, Thoennessen M (2013). "Discovery of actinium, thorium, protactinium, and uranium isotopes". Atomic Data and Nuclear Data Tables. 99 (3): 345–364. arXiv:1203.1194. Bibcode:2013ADNDT..99..345F. doi:10.1016/j.adt.2012.03.002. ISSN 0092-640X. S2CID 97142872.
- ^ Lewis SL, Bucher L, Heitkemper M, Harding MM (2017). Medical-Surgical Nursing: Assessment and Management of Clinical Problems (10th ed.). Elsevier. ISBN 978-0-323-32852-4.
- ^ Marques IA, Neves AR, Abrantes AM, Pires AS, Tavares-da-Silva E, Figueiredo A, Botelho MF (July 2018). "Targeted alpha therapy using Radium-223: From physics to biological effects". Cancer Treatment Reviews. 68: 47–54. doi:10.1016/j.ctrv.2018.05.011. PMID 29859504. S2CID 44144271.
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