Potassium iodide

Potassium iodide
Clinical data
Trade names	Iosat, Thyrosafe, Thyroshield, others
Other names	SSKI
AHFS/Drugs.com	Monograph
License data	US DailyMed: Potassium iodide;
Routes of; administration	By mouth
ATC code	R05CA02 (WHO) S01XA04 (WHO), V03AB21 (WHO);
Legal status
Legal status	US: WARNINGOTC;
Identifiers
	IUPAC name Potassium iodide;
CAS Number	7681-11-0 ;
PubChem CID	4875;
DrugBank	DB06715;
ChemSpider	4709;
UNII	1C4QK22F9J;
KEGG	D01016;
ChEBI	CHEBI:8346;
ChEMBL	ChEMBL1141;
CompTox Dashboard (EPA)	DTXSID7034836 ;
ECHA InfoCard	100.028.782
Chemical and physical data
Formula	KI
3D model (JSmol)	Interactive image;
Density	3.13 g/cm3
Melting point	681 °C (1,258 °F)
Boiling point	1,330 °C (2,430 °F)
Solubility in water	1280 mg/mL (0 °C (32 °F)) ; 1400 mg/mL (20 °C (68 °F)) ; 1760 mg/mL (60 °C (140 °F)) ; 2060 mg/mL (100 °C (212 °F)) 2 0 0
	SMILES [K+].[I-];
	InChI InChI=1S/HI.K/h1H;/q;+1/p-1 ; Key:NLKNQRATVPKPDG-UHFFFAOYSA-M;

Potassium iodide is a chemical compound, medication, and dietary supplement.^[4]^[5] It is a medication used for treating hyperthyroidism, in radiation emergencies, and for protecting the thyroid gland when certain types of radiopharmaceuticals are used.^[6] In the third world it is also used for treating skin sporotrichosis and phycomycosis.^[6]^[7] It is a supplement used by people with low dietary intake of iodine.^[5] It is administered orally.^[6]

Common side effects include vomiting, diarrhea, abdominal pain, rash, and swelling of the salivary glands.^[6] Other side effects include allergic reactions, headache, goitre, and depression.^[7] While use during pregnancy may harm the baby, its use is still recommended in radiation emergencies.^[6] Potassium iodide has the chemical formula K I.^[8] Commercially it is made by mixing potassium hydroxide with iodine.^[9]^[10]

Potassium iodide has been used medically since at least 1820.^[11] It is on the World Health Organization's List of Essential Medicines.^[12] Potassium iodide is available as a generic medication and over the counter.^[13] Potassium iodide is also used for the iodization of salt.^[5]

^ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^ "Density of Potassium iodide". Aqua-Calc. Archived from the original on 21 April 2021. Retrieved 21 April 2021.
^ "Potassium Iodide" (PDF). Archived (PDF) from the original on 10 May 2019. Retrieved 10 May 2019.
^ National Research Council, Division on Earth and Life Studies, Board on Radiation Effects Research, Committee to Assess the Distribution and Administration of Potassium Iodide in the Event of a Nuclear Incident (2004). Distribution and Administration of Potassium Iodide in the Event of a Nuclear Incident. National Academies Press. p. 10. ISBN 978-0-309-09098-8. Archived from the original on 18 September 2017.
^ ^a ^b ^c Stwertka A (2002). A Guide to the Elements. Oxford University Press, USA. p. 137. ISBN 978-0-19-515026-1. Archived from the original on 14 September 2017.
^ ^a ^b ^c ^d ^e "Potassium Iodide". The American Society of Health-System Pharmacists. Archived from the original on 16 January 2017. Retrieved 8 January 2017.
^ ^a ^b World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 390. hdl:10665/44053. ISBN 978-92-4-154765-9.
^ Ensminger ME, Ensminger AH (1993). Foods & Nutrition Encyclopedia, Two Volume Set (s ed.). CRC Press. p. 16. ISBN 978-0-8493-8980-1. Archived from the original on 13 August 2017.
^ Kaiho T (2014). Iodine Chemistry and Applications. John Wiley & Sons. p. 57. ISBN 978-1-118-87865-1. Archived from the original on 13 August 2017.
^ Center for Drug Evaluation and Research (December 2001). "Potassium Iodide as a Thyroid Blocking Agent in Radiation Emergencies". U.S. Food and Drug Administration. Archived from the original on 19 August 2020. Retrieved 22 August 2020.
^ Oriel JD (2012). The Scars of Venus: A History of Venereology. Springer Science & Business Media. p. 87. ISBN 978-1-4471-2068-1. Archived from the original on 14 September 2017.
^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^ Hamilton R (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 224. ISBN 978-1-284-05756-0.

[FDA-AllBoxedWarnings-1] "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.

[2] "Density of Potassium iodide". Aqua-Calc. Archived from the original on 21 April 2021. Retrieved 21 April 2021.

[3] "Potassium Iodide" (PDF). Archived (PDF) from the original on 10 May 2019. Retrieved 10 May 2019.

[4] National Research Council, Division on Earth and Life Studies, Board on Radiation Effects Research, Committee to Assess the Distribution and Administration of Potassium Iodide in the Event of a Nuclear Incident (2004). Distribution and Administration of Potassium Iodide in the Event of a Nuclear Incident. National Academies Press. p. 10. ISBN 978-0-309-09098-8. Archived from the original on 18 September 2017.

[St2002-5] Stwertka A (2002). A Guide to the Elements. Oxford University Press, USA. p. 137. ISBN 978-0-19-515026-1. Archived from the original on 14 September 2017.

[AHFS2017-6] "Potassium Iodide". The American Society of Health-System Pharmacists. Archived from the original on 16 January 2017. Retrieved 8 January 2017.

[WHO2008-7] World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 390. hdl:10665/44053. ISBN 978-92-4-154765-9.

[8] Ensminger ME, Ensminger AH (1993). Foods & Nutrition Encyclopedia, Two Volume Set (s ed.). CRC Press. p. 16. ISBN 978-0-8493-8980-1. Archived from the original on 13 August 2017.

[9] Kaiho T (2014). Iodine Chemistry and Applications. John Wiley & Sons. p. 57. ISBN 978-1-118-87865-1. Archived from the original on 13 August 2017.

[10] Center for Drug Evaluation and Research (December 2001). "Potassium Iodide as a Thyroid Blocking Agent in Radiation Emergencies". U.S. Food and Drug Administration. Archived from the original on 19 August 2020. Retrieved 22 August 2020.

[Or2012-11] Oriel JD (2012). The Scars of Venus: A History of Venereology. Springer Science & Business Media. p. 87. ISBN 978-1-4471-2068-1. Archived from the original on 14 September 2017.

[WHO21st-12] World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

[Ric2015-13] Hamilton R (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 224. ISBN 978-1-284-05756-0.

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