Non-Hodgkin lymphoma

Non-Hodgkin lymphoma
Other names	Non-Hodgkin disease
Micrograph of mantle cell lymphoma, a type of non-Hodgkin lymphoma. Terminal ileum. H&E stain.
Specialty	Hematology and oncology
Symptoms	Enlarged lymph nodes, fever, night sweats, weight loss, tiredness, itching[1]
Usual onset	65–75 years old[2]
Risk factors	Poor immune function, autoimmune diseases, Helicobacter pylori infection, hepatitis C, obesity, Epstein-Barr virus infection[1][3]
Diagnostic method	Bone marrow or lymph node biopsy[1]
Treatment	Chemotherapy, radiation, immunotherapy, targeted therapy, stem cell transplantation, surgery, watchful waiting[1]
Prognosis	Five-year survival rate 71% (USA)[2]
Frequency	4.3 million (affected during 2015)[4]
Deaths	231,400 (2015)[5]

Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas.^[1] Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness.^[1] Other symptoms may include bone pain, chest pain, or itchiness.^[1] Some forms are slow-growing while others are fast-growing.^[1] Unlike Hodgkin lymphoma, which spreads contiguously, NHL is largely a systemic illness.^[6]