Gold-containing drugs

Sodium aurothiomalate
Auranofin

Gold-containing drugs are pharmaceuticals that contain gold. Sometimes these species are referred to as "gold salts". "Chrysotherapy" and "aurotherapy" are the applications of gold compounds to medicine.[1] Research on the medicinal effects of gold began in 1935,[2] primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis. The use of gold compounds has decreased since the 1980s because of numerous side effects and monitoring requirements, limited efficacy, and very slow onset of action. Most chemical compounds of gold, including some of the drugs discussed below, are not salts, but are examples of metal thiolate complexes.

  1. ^ Shaw CF (September 1999). "Gold-based therapeutic agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.
  2. ^ Forestier J (May 1935). "Rheumatoid arthritis and its treatment with gold salts - results of six years experience". J Lab Clin Med. 20 (8): 827–840.

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