Theoretical metabolic state
Estrogen dominance (ED) is a theory about a metabolic state where the level of estrogen outweighs the level of progesterone in the body. This is said to be caused by a decrease in progesterone without a subsequent decrease in estrogen.
The theory was proposed first by Dr Raymond Peat. [1] John R. Lee learned about progesterone and estrogen dominance when he attended a lecture by Dr. Raymond Peat. [2]John R. Lee and Virginia Hopkins wrote about estrogen dominance in their 1996 book, What Your Doctor May Not Tell You About Menopause: The Breakthrough Book on Natural Progesterone. In their book Lee and Hopkins assert that ED causes fatigue, depression, anxiety, low libido, weight gain specifically in the midsection, water retention, headaches, mood swings, white spots on fingernails, and fibrocystic breasts.[3] The book criticizes estrogen replacement therapy and proposes the use of "natural progesterone" for menopausal women to alleviate a variety of complaints. Lee's theories have been criticized for being inadequately supported through science, being primarily based on anecdotal evidence with no rigorous research supporting them.[4]
Estrogen dominance can affect both men and women.
